collagen vascular disease


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Collagen Vascular Diseases

Summary: Collagen Vascular diseases resulted from immune malfunction which also affect other organs of the body.

Collagen is a strong, glue-like protein that represents 30 % of body protein and shapes the structure of tendons, bones, and connective tissues. Immune system malfunction can affect these structures. This is identified as collagen vascular disease. The collagen vascular diseases include: rheumatoid arthritis, systemic lupus erythematosus, scleroderma, dermatomyositis, and polyarteritis nodosa.

Rheumatoid arthritis is a never-ending disease that causes inflammation of the joints and surrounding tissues. It can also affect other organs. Our body's immune system normally fights off foreign substances, like viruses but, in an autoimmune disease, the immune system confuses healthy tissue for foreign substances. As a result, the body attacks itself. This collagen vascular disease can occur at any age usually in people between the ages 25 and 55. The course of the severity of the disease can differ significantly. Infection, genes, and hormones may add to the illness. Rheumatoid arthritis usually affects joints on both sides of the body. Wrists, knees, fingers, feet, and ankles-the most commonly affected.

Systemic lupus erythematosus is a chronic, inflammatory autoimmune disorder. It can affect the skin, joints, kidneys, and other organs. Many researchers suspect it occurs after infection with an organism that looks similar to particular protein in the body which are later mistaken for the organism and wrongly targeted for attack. This disease may also caused by certain drugs. If it occurs, it is called drug-induced lupus erythematosus and is reversible when the medication is stopped. This can also occur at any age but usually appears in people between 10-50 years old.

Scleroderma is a diffuse connective tissue disease characterized by changes in the skin, blood vessels, skeletal muscles, and internal organs. The course and severity of this collagen vascular disease varies widely in those affected. Extra collagen deposits in the skin and other organs create the symptoms. Damage to small blood vessels within the skin and affected orgasm also occur. In the skin, ulceration, calcification, and changes in pigmentation may occur. Systemic features may include fibrosis and degeneration of the heart lungs, kidneys, and gastrointestinal tract. This usually affects in people aged 30 to 50 years old and affects more on women than men.

Dermatomyositis is a connective tissue disease that is characterized by inflammation of the muscles and skin. No identified cause of this disease yet it is speculated that a viral infection of the skeletal muscle may cause the disease. This collagen vascular disease can affect people at any age, usually at their 40 to 60 years old or 5-15 for children. Muscle weakness may occur slowly, difficulty in raising you arms over the head, raising from a sitting position, and climbing stairs. Dusky, red rash may appear on your face, neck, shoulders, upper chest, and back.

Polyarteritis nodosa is a serious blood vessel disease. Small and medium-sized arteries become swollen and damaged when attacked by rouge immune system. Adults are more affected than children. This collagen vascular disease damages the tissue supplied by the affected arteries because they are not receiving enough oxygen and nourishment without a proper blood supply. Symptoms of this disease result from damaged to affected organs, regularly the skin, heart, kidneys, and nervous system.

These collagen vascular diseases don't have any identified explanations as to the causes of these illnesses but they usually affect more women compared to men. What is so scary about these illnesses is that it affects other organs of our body which makes things more complicated than it already is.
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